CBD with Intelligent NanoDelivery SystemTM
• Full Spectrum ( max. 0,3% THC ) or Broad Spectrum ( 0% THC ) Hemp derived organic Oil.
• Concentrated formulas with other helpful ingredients • Ingredients nano-sized for better penetration.
• Stable in various base formulas.
• GMP quality control.
• Not tested on animals, Paraben-free, Eco-friendly.
Maoli Nano Brain Booster formula:
Designed to create a sense of focus and brain performance stimulation throughout the day.
Ingredients: MCT Coconut Oil, INDSCBD oil, Tumeric RooteExtract, Ginseng, Gotu Kola, Ginko Biloba extract, Brahimi extract, DHA/EPA, Acetyl L-carnitine, Alpha Lioplic acid and DMAE.
INDSCBD Oil Ingredients: Purified water, full spectrum CBD oil, lipids, surfactants, fatty acids.
CannaBinoiDs might improve our brain function:
First of all, it is important to realize that most of what is written here is theory, and most studies are done on mice, not humans! Also, there is huge difficulty in saying a particular medication is a preventative, especially when it comes to something like aging!
With this being said, there are some studies showing that low doses of some central nervous system (CNS) stimulants enhance cognition in healthy people. Agonists and antagonists of dopamine receptor D1 and/or adrenoceptor A2 in the prefrontal cortex demonstrate cognition-enhancing effects. Overstimulation can cause cognitive deficits.
The above can apply to cannabinoids, at least to a certain extent. Moreover, cannabinoids are more well-tolerated than many medications, even innocuous ones like ibuprofen. Whilst it is possible that taking too much THC may cause some cognitive deficits (especially in young people), unlike many CNS stimulants, overdose on cannabinoids alone will not kill you.
Here’s some ways of using cannabinoids as a possible nootropic (including rehashing some of what has been written above):
- Think of age – younger people are generally more sensitive to THC. For older people, and especially those approaching middle-age or their senior years, a small amount of THC may be beneficial.
- Utilize the entourage effect to your benefit – pinene, CBD and small doses of THCV (larger doses of THCV are a CB1 receptor agonist) may buffer against the negative effects of THC. CB2 receptor agonists like beta-caryophyllene (found in black pepper) can also potentially exponentiate THC’s and CBD’s stress-busting, analgesic and anti-inflammatory effects.
- Don’t demonize or avoid THC entirely – small doses have stress-busting and anti-inflammatory effects. This can possibly make small amounts of THC great for treating nausea or post-exercise inflammation, for example, especially when combined with CBD and other cannabinoids and terpenes (e.g. limonene, linalool). Also, some types of cancer treatment may require high doses of THC, so it is a compound that is often unfairly called “non-medical”.
- Keep your mind and body as active as possible – a good diet, exercise, playing an instrument, learning new skills (e.g. drawing, dancing), and playing board games & quizzes can all help slow cell aging. Some slight euphoria from cannabinoids may even help you enjoy these activities even more!
- Different methods of ingestion may be best to take advantage of cannabinoids’ possible nootropic effects – tinctures and possibly even microdosing using high-quality vaporizers (e.g. Volcano Vaporizers, not necessarily pre-filled vape pens) may be best.
- Tetrahydrocannabinolic acid (THCA) is the acidic precursor to THC, and is non-psychoactive. THCA may also have its anti-inflammatory properties, and could be useful, especially for younger people. However, as THCA does not bind to either CB1 or CB2 receptors, it may actually be a small amount of THC that is doing the work! There could be some sort of way THCA (or an analogue of THCA, THCA-B) that exerts its effects by slowly “filtering” THC into cells, but this is all supposition. Raphael Mechoulam rightfully describes THCA as “diabolical”, as nobody is sure exactly how it works, if it works at all!
Turmeric Root extract, interestingly, curcumin can increase brain levels of BDNF. By doing this, it may be effective in delaying or even reversing many brain diseases and age-related decreases in brain function. It may also improve memory and make you smarter, which seems logical given its effects on BDNF levels.
Ginseng, could help improve brain functions like memory, behavior and mood. Some testtube and animal studies show that components in ginseng, like ginsenosides and compound K, could protect the brain against damage caused by free radicals.
Gotu Kola, has the ability to enhance memory and nerve function, which gives it potential in treating Alzheimer's disease. In fact, one 2012 study on mice found that gotu kola extract had a positive effect on behavioral abnormalities in mice with Alzheimer's disease.
Ginko Biloba extract, researchers believe that ginkgo improves cognitive function because it promotes good blood circulation in the brain and protects the brain andother parts from neuronal damage. However, other research suggests that ginkgo may not improve memory among people who are healthy.
Brahmi extract, contains active compounds called bacosides, which protect your brainfrom oxidative stress and improve signaling in your hippocampus, an area of your brain in which memories are processed
DHA (Docosahexaenoic acid) / EPA (Eicosapentaenoic acid), studies show that higher blood DHA levels are linked to areduced risk of dementia and Alzheimer's ( 56 ). DHA is essential for brain and eye development. As such, low levels may disrupt brain function and are linked to an increased risk of memory complaints, dementia, and Alzheimer's disease.
Acetyl L-carnitine, it is involved in fatty acid metabolism and may improve several aspects of brain health, including mitochondrial function, activity of the neurotransmitter acetylcholine, and possibly cognition. However the data suggests that it does not provide a substantial cognitive benefit to patients with dementia.
Alpha Lipoic acid, is also a potent antioxidant, neutralizing potentially harmful chemicals called free radicals—and the acid has been shown to increase the production ofacetylcholine, a brain chemical that is a key component of memory.
DMAE, is thought to work by increasing production of acetylcholine (Ach), aneurotransmitter that's crucial for helping nerve cells send signals. Ach helps regulate many functions controlled by the brain, including REM sleep, muscle contractions, and pain responses.
All about CannaBinoiDs
Hemp/Cannabis has been used by civilizations all over the world for
thousands of years. The history of this plant goes as far back as 12,000 B.C.E. Written language developed on hemp paper, the first woven clothes were made of hemp fiber, and modern medicine evolved from extractions of hemp flowers. CBD is non-psychoactive. Scientific and clinical research suggests CBD’s potential as a treatment for arthritis, diabetes, alcoholism, MS, chronic pain, schizophrenia, PTSD, depression, antibiotic-resistant infections, epilepsy, and otherneurological disorders.
How could CannaBinoiDs work?
The human body’s EndoCannabinoid System produces naturally occurring cannabinoids, Anadamide and 2-AG(2-atachidonoylglycerol), which stimulate the body’s
cannabinoid receptors. Cannabinoid receptors (CB1, CB2, TRPV1, TRPA1 and TRPV4) are present on multiple cell types in the human skin (fibroblasts, keratinocytes, immune cells, neurons, subcutaneous fat cells and muscle layers). These receptors engage in “retrograde signaling,” that inhibits immune response, reduces inflammation, relaxes muscles, lowers blood pressure, increases blood flow and normalizes over-stimulated nerves. In the epidermis, CBD inhibits keratinocyte proliferation, decreases keratinization and suppresses cornified envelope formation, promotes epidermal differentiation, and inhibits proliferation of keratinocytes. Studies have also shown CBD can improve reduced barrier function, increase hydration, reduce moisture loss, inhibit dermal fibrosis, suppress UV-B induced skin damage, and decrease inflammation.