CBD with Intelligent NanoDelivery SystemTM
• Full Spectrum ( max. 0,3% THC ) or Broad Spectrum ( 0% THC ) Hemp derived organic Oil.
• Concentrated formulas with other helpful ingredients • Ingredients nano-sized for better penetration.
• Stable in various base formulas.
• GMP quality control.
• Not tested on animals, Paraben-free, Eco-friendly.
Maoli Nano Pain formula:
Designed to create a sense of well-being and comfort to encourage deep, rejuventating sleep.
Ingredients: MCT Coconut Oil, INDSCBD oil, Hops, Kava, Lavender, Linden Flower, Melatonin, Passionflower, Valerian.
INDSCBD Oil Ingredients: Purified water, full spectrum CBD oil, lipids, surfactants, fatty acids.
CannaBinoiDs might improve the sleep cycle:
Taken together, research suggests that short-term use of can- nabis may have a therapeutic impact on sleep, specifically related to sleep onset latency and slow wave sleep. However, long-term chronic use is associated with habituation to the sleep-enhancing benefits and is associated with in- creased risk for cannabis dependence. Sleep disruption (self- reported and objective) is a primary withdrawal symptom from cannabis and may play a role in cannabis lapse/relapse during cessation attempts. While this work has been focused on the cannabis flower, recent work has suggested that specif- ic cannabinoids (THC and CBD) have a differential impact on sleep. This is further influenced by the dosage, ratio of canna- binoids, timing of administration, and route of administration. Initial work examining specific cannabinoids suggests a po- tential therapeutic effect of high-dose CBD and low-dose THC for sleep. What follows is an overview of the impact of cannabis, and specific cannabinoids, on a number of sleep disorders for which this research has been examined.
Scientific research shows that hops, with its natural sedative effects, can increase sleep time. Hops also helps to lower body temperaturefalling core body temperature is one important physiological step toward sleep. Hops has also been shown to reinforce the body's daily bio rhythms of rest and activity.
When taken for anxiety or stress, kava does not interfere with mental sharpness. When taken for sleep problems, kava promotes deep sleep without affecting restful REM sleep. Kava may be used instead of prescription antianxiety drugs, such as benzodiazepines and tricyclic antidepressants.
Lavender works as an anxiolytic (an anxiety reliever) and as a sedative, to increase relaxation and calm, and help bring about sleep. Lavender interacts with the neurotransmitter GABA to help quiet the brain and nervous system activity, reducing agitation, anger, aggression, and restlessness.
Linden is best known to help with mild insomnia and anxiety. One of the active ingredients in linden is an essential oil called farnesol, which helps relax the cardiovascular system. This may have a positive impact on arrhythmias while also curbing stress. Most people report feeling relaxed, and even drowsy.
Melatonin is a natural hormone that the brain releases in response to changes in light. It helps regulate the body's internal clock, signaling that it is time to go to sleep. Melatonin supplements may help with a wide range of sleep issues, including insomnia, shift work sleep disorder, and sleep problems in children.
Incarnata has many common names, including purple passionflower and maypop. Early studies suggest it might help relieve insomnia and anxiety. It appears to boost the level of gamma-aminobutyric acid (GABA) in your brain. This compound lowers brain activity, which may help you relax and sleep better.
How does valerian root work? Researchers aren't sure how valerian root works to ease insomnia and anxiety. They think it subtly increases the levels of a chemical known as gamma aminobutyric acid (GABA) in the brain. GABA contributes to a calming effect in the body.
All about CannaBinoiDs
Hemp/Cannabis has been used by civilizations all over the world for
thousands of years. The history of this plant goes as far back as 12,000 B.C.E. Written language developed on hemp paper, the first woven clothes were made of hemp fiber, and modern medicine evolved from extractions of hemp flowers. CBD is non-psychoactive. Scientific and clinical research suggests CBD’s potential as a treatment for arthritis, diabetes, alcoholism, MS, chronic pain, schizophrenia, PTSD, depression, antibiotic-resistant infections, epilepsy, and otherneurological disorders.
How could CannaBinoiDs work?
The human body’s EndoCannabinoid System produces naturally occurring cannabinoids, Anadamide and 2-AG(2-atachidonoylglycerol), which stimulate the body’s
cannabinoid receptors. Cannabinoid receptors (CB1, CB2, TRPV1, TRPA1 and TRPV4) are present on multiple cell types in the human skin (fibroblasts, keratinocytes, immune cells, neurons, subcutaneous fat cells and muscle layers). These receptors engage in “retrograde signaling,” that inhibits immune response, reduces inflammation, relaxes muscles, lowers blood pressure, increases blood flow and normalizes over-stimulated nerves. In the epidermis, CBD inhibits keratinocyte proliferation, decreases keratinization and suppresses cornified envelope formation, promotes epidermal differentiation, and inhibits proliferation of keratinocytes. Studies have also shown CBD can improve reduced barrier function, increase hydration, reduce moisture loss, inhibit dermal fibrosis, suppress UV-B induced skin damage, and decrease inflammation.