MaoliCare is very proud and honored to have joint Nanoshell Company as their European partner! Agnes Ostafin is head of the Ostafin Nano-Biotechnology Group at the University of Utah and an assistant professor in the Department of Chemical and Bio-Molecular Engineering at the University of Notre Dame.

Dr. Agnes Ostafin · Founder/Partner
MS Engineering Management, Drexel University, US
Ph.D. in Chemical Physics, University of Minnesota, US

Agnes has over 25 years of nanobiotechnology experience involving synthesis, characterization, chemical and radiation damage, and development of supporting technologies.





What is Nano? Nano is a word that describes objects with a size of only one billionth of a meter, or the length your fingernail grows in one second. The head of a pin is about 1 million nanometers across. You can’t see a nano-sized object with your eye, but you can with special laboratory tools. Scientists have been studying the properties of materials made to be nano-sized and have found interesting things about how these materials behave, in many cases, a lot differently that you would expect. Some of these unique features have a lot of importance in industries such as aerospace, technology, medicine, food and cosmetics.


Why use Nano in your products? You have probably heard that Nano is new and exciting, but why? Materials prepared in nano-sized form tend to be easier to get to places where they need to go: they can mix easier with other things, they can penetrate deeper, and are close to the size of things that living cells recognize and thrive with. Taking this all together means that substances can be more effective, requiring less material at a lower cost to produce. It lowers the risk of adverse effects and is better for the environment. This is good for the manufacturer and the end-user.


How is Nano manufactured? Depending on the substance different methods are used to make nano-sized products. Generally, you can divide nano into hard and soft nano. Hard nano includes metals like gold, silver, copper, zeolites, and pearl powder. These materials can be collected from the environment, usually in large pieces, and mechanically broken with friction or electric energy until the pieces reach nano-size. Depending on the amount of material that is made, it might be hard to get to the size you need or make a perfect specimen. For some materials, like silver and gold nano-sized materials can also be made chemically starting with dissolved atoms, and doing chemistry to bring them together until a nano-size is reached. This method makes it easier to get the smallest nanosizes, but may require some unpleasant chemicals to keep the pieces from growing further during storage and mixing in a product. Soft nano includes liposomes, emulsions, fat or polymer particles as long as their size is nano. These materials are made by taking advantage of the natural tendency of these molecules to assemble into ordered and layered structures. Conveniently Nature has also made living cells uniquely responsive to these types of materials and similar things are made and used in your body to shuttle food, hormones and other things around to keep you healthy and alive.


Why Intelligent-NanoDelivery? Intelligent NanoDelivery uses a combination of hard and soft nano processing methods to make unique materials with excellent bioavailability, penetration, function and stability. By using proprietary mixtures of biologically safe and beneficial materials, we control penetration, blending, bioavailability and other important features, avoiding adverse chemical effects. By blending various kinds of nano we can create a cocktail of nutrients similar to what the body would normally make on its own and get them to their destination with minimal waste. Our formulas are excellent ingredients for skin, hair and other body care products, and can be integrated into a client’s formula or end product with excellent results. Please give our products a try.



Hemp has been used by civilizations all over the world for thousands of years. The history of this plant goes as far back as 12,000 B.C.E. Written language developed on hemp paper, the first woven clothes were made of hemp fiber, and modern medicine evolved from extractions of hemp flowers. CBD is non-psychoactive. Scientific and clinical research suggests CBD’s potential as a treatment for arthritis, diabetes, alcoholism, MS, chronic pain, schizophrenia, PTSD, depression, antibiotic-resistant infections, epilepsy, and other neurological disorders.


How does CBD work? The human body’s EndoCannabinoid System produces naturally occurring cannabinoids, Anadamide and 2-AG(2 atachidonoylglycerol), which stimulate the body’s cannabinoid receptors. Cannabinoid receptors (CB1, CB2, TRPV1, TRPA1 and TRPV4) are present on multiple cell types in the human skin (fibroblasts, keratinocytes, immune cells, neurons, subcutaneous fat cells and muscle layers). These receptors engage in “retrograde signaling,” that inhibits immune response, reduces inflammation, relaxes muscles, lowers blood pressure, increases blood flow and normalizes over-stimulated nerves. In the epidermis, CBD inhibits keratinocyte proliferation, decreases keratinization and suppresses cornified envelope formation, promotes epidermal differentiation, and inhibits proliferation of keratinocytes. Studies have also shown CBD can improve reduced barrier function, increase hydration, reduce moisture loss, inhibit dermal fibrosis, suppress UV-B induced skin damage, and decrease inflammation.


ALL-NATURAL Phyto-cannabinoid rich hemp oil. Contains the full spectrum of naturally-occuring Phyto-cannabinoid, terpenes, flavanoids and essential amino acids.


Intelligent NanoDelivery System CBD oil (INDS CBD Oil)

Additive for personal care products. Ingredients: Purified water, full spectrum CBD-rich hemp oil, lipids, surfactants, fatty acids.

Interested in this product?  Contact us!



Pain formula

Designed to fight pain, while soothing overstimulated skin. Ingredients: Purified water, INDS CBD Oil, Arnica, Boswelia, Clove, Devil’s Claw, Feverfew, White Willow Bark.

Interested in this product?  Contact us!



Acne Fighter

Designed to fight acne organically and maintain clear complexion. Ingredients: Purified water, INDS CBD oil, Aloe Vera Juice, Calendula, Cucumber, Grape Seed oil, Moringa oil, Neem oil.

Interested in this product?  Contact us!



Relaxation formula

Designed to provide an uplifting atmosphere and effective ingredients through out the day. Ingredients: Purified water, INDS CBD oil, 5-HTP, Chamomile, Folic Acid, Ginko Biloba, Ginseng, Lemon Balm, St. John Wort

Interested in this product?  Contact us!



Nausea formula

Designed to be used in skin balms to control unpleasant symptoms. Ingredients: Purified water, INDS CBD oil, Chamomile, Cinnamon, Fennel, Ginger, Peppermint.

Interested in this product?  Contact us!



Sleep formula

Designed to create a sense of well-being and comfort to encourage deep, rejuventating sleep. Ingredients: Purified water, INDS CBD oil, Hops, Kava, Lavender, Linden Flower, Melatonin, Passionflower, Valerian

Interested in this product?  Contact us!



CBD with Intelligent NanoDelivery System:

  • No THC, all natural, phytocannabinoid-rich, hemp oil
  • Concentrated formulas with other helpful ingredients
  • Ingredients nano-sized for better effectiveness
  • Stable in various base formulas
  • GMP quality control
  • Not tested on animals, Paraben-free, Eco-friendly,

    *****Statements regarding these products have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease. Please consult your health care provider about potential interactions or complications before using these products.*****



The Intelligent NanoDelivery System for Personal care Products:


The Intelligent NanoDelivery System for Personal Care Products provides a variety of innovative, effective and safe ingredients in an easy-to-blend nano-sized package usable in any product formulation. Using the latest nanotechnology advances, clinically proven and safe ingredients, and specialized delivery systems, the Intelligent NanoDelivery System will enhance the effectiveness and aesthetics of fine cosmetics and personal care products.














Concept Behind the Intelligent NanoDelivery System


Scientists behind the Intelligent NanoDelivery System for Personal Care Products have utilized state-of-the-art advances in pharmaceutical transdermal drug delivery, to produce tailorable, nano-sized delivery vehicles that penetrate to selected depths of skin or the hair cuticle to deliver beneficial substances. This allows appropriate support of the skin and hair according to its structure and developmental state. Confocal microscope imaging results have been used to study the dermal penetration of various Intelligent NanoDelivery System products compared with “hard” gold and calcium carbonate nanoparticles. Softer, deformable mixtures penetrate deeper and deliver ingredients effectively.


The products in the Intelligent NanoDelivery System can be mixed to create an intelligent gradient of nutrients that truly supports skin regeneration, repair and protection. Regular use will lead to real, long-term improvements in the skin’s and hair’s appearance and texture.

Ready-to-Use and Worry-free


The Intelligent NanoDelivery System provides ready-to use, nano-sized, ingredients intended for mixing with a customer’s formulation. Depending on what you would like to achieve, a mixture of one or more products from this system can be used to create a unique and effective product. Pre-mixed blends tailored for dermal healing, dermal support, dermal softening, and dermal renew are available. We use consistent, simple formulas, medical and food grade bio-friendly, quality ingredients, minimal preservatives, sterile, traceable processing, and stringent testing of safety and function. We can also address mixing challenges specific to your product or application, by creating an appropriate delivery system tailored for your formulations and desired outcome. This is done by selecting a size, outside, charge, internal contents, and best combination of components.







Intelligent Nano Delivery System was created as a response to the growing market demands in the field of personal care products. Our solutions help reduce production costs, increase the quality and efficiency of production of the companies that implement it.

The benefits of working with Nanoshell Company are not just our products. With us, every customer has the opportunity to choose their own configuration, tailored to his or her individual and unique needs. Nanoshell Company prides itself on its openness, honesty and care for our  partner's interests. We offer products that have proven themselves in many investments among global market leaders. Remember that you gain a partner when doing business with Nanoshell.