CBD with Intelligent NanoDelivery SystemTM
• Full Spectrum ( max. 0,3% THC ) or Broad Spectrum ( 0% THC ) Hemp derived organic Oil.
• Concentrated formulas with other helpful ingredients • Ingredients nano-sized for better penetration.
• Stable in various base formulas.
• GMP quality control.
• Not tested on animals, Paraben-free, Eco-friendly.
Maoli Nano Pain formula:
Designed to maximize pain relief, while soothing overstimulated skin.
Ingredients: MCT Coconut Oil, INDSCBD oil, Arnica, Boswelia, Clove, Devil’s Claw, Feverfew, White Willow Bark
INDSCBD Oil Ingredients: Purified water, Broad Spectrum CBD oil, lipids, surfactants, fatty acids.
How can CannaBinoiDs reduce pain?:
The mechanisms of the analgesic effect of cannabinoids include inhibition of the release of neurotransmitters and neuropeptides from presynaptic nerve endings, modulation of postsynaptic neuron excitability, activation of descending inhibitory painpathways, and reduction of neural inflammation.
Arnica preparations have shown wound healing, antiseptic, anti-inflammatory, and pain relieving properties. Arnica's actions may be due to two chemicals called helenalin and dihyrdohelenalin.
By now, everyone’s heard of turmeric and its remarkable anti-inflammatory benefits. But here’s the newest herb you’ve never heard of that may be even better than turmeric at easing pain, reducing inflammation, and protecting against cancer.
Boswellia, also known as Indian frankincense, comes from the Boswellia serrata tree, native to India. It’s been used for thousands of years in Ayurveda and other traditional healing systems to treat conditions like arthritis, pain, fever, and heart disease. Other types of boswellia, including Boswellia sacra, Boswellia frereana, and Boswellia carteri, have similar effects.
It’s similar to turmeric in mechanisms of action and conditions treated; used together, curcumin and boswellia may have synergistic effects that make them more powerful than using each alone. In one study, a combination of boswellia and turmeric was significantly more effective in reducing pain than the prescription NSAID celecoxib, commonly used for arthritis.
The anti-inflammatory benefits of boswellia come mainly from boswellic acids and terpenes, strong-smelling antioxidant compounds that are also found in citrus, eucalyptus, mint, and other plants. Studies suggest boswellic acids work by inhibiting the synthesis of a specific pro-inflammatory enzyme, 5-lipoxygenase (5-LO). One of the most important boswellic acids is acetyl-11-keto-beta-boswellic acid, or AKBA.
Clove contains the active ingredient eugenol, which is a natural anesthetic. It helps numb and reduce pain to ease a toothache. Eugenol also has natural anti-inflammatory properties. It may reduce swelling and irritation in the affected area.
Along with anti-inflammatory effects, devil's claw shows potential as a pain reliever, particularly for lower back pain. Researchers attribute this to harpagoside, an active plant compound in devil's claw.
It's been used as a pain reliever for centuries. Its feathery, aromatic leaves are used to prevent migraine headaches. Experts say that parthenolide and other ingredients in feverfew get in the way of serotonin and prostaglandin. These are natural substances that dilate the blood vessels.
White Willow Bark:
The bark of white willow contains salicin, which is a chemical similar to aspirin (acetylsalicylic acid). In combination with the herb's powerful anti-inflammatory plant compounds (called flavonoids), salicin is thought to be responsible for the pain-relieving and anti-inflammatory effects of the herb.
All about CannaBinoiDs
Hemp/Cannabis has been used by civilizations all over the world for
thousands of years. The history of this plant goes as far back as 12,000 B.C.E. Written language developed on hemp paper, the first woven clothes were made of hemp fiber, and modern medicine evolved from extractions of hemp flowers. CBD is non-psychoactive. Scientific and clinical research suggests CBD’s potential as a treatment for arthritis, diabetes, alcoholism, MS, chronic pain, schizophrenia, PTSD, depression, antibiotic-resistant infections, epilepsy, and otherneurological disorders.
How could CannaBinoiDs work?
The human body’s EndoCannabinoid System produces naturally occurring cannabinoids, Anadamide and 2-AG(2-atachidonoylglycerol), which stimulate the body’s
cannabinoid receptors. Cannabinoid receptors (CB1, CB2, TRPV1, TRPA1 and TRPV4) are present on multiple cell types in the human skin (fibroblasts, keratinocytes, immune cells, neurons, subcutaneous fat cells and muscle layers). These receptors engage in “retrograde signaling,” that inhibits immune response, reduces inflammation, relaxes muscles, lowers blood pressure, increases blood flow and normalizes over-stimulated nerves. In the epidermis, CBD inhibits keratinocyte proliferation, decreases keratinization and suppresses cornified envelope formation, promotes epidermal differentiation, and inhibits proliferation of keratinocytes. Studies have also shown CBD can improve reduced barrier function, increase hydration, reduce moisture loss, inhibit dermal fibrosis, suppress UV-B induced skin damage, and decrease inflammation.