CBD with Intelligent NanoDelivery SystemTM
• Full Spectrum ( max. 0,3% THC ) or Broad Spectrum ( 0% THC ) Hemp derived organic Oil.
• Concentrated formulas with other helpful ingredients • Ingredients nano-sized for better penetration.
• Stable in various base formulas.
• GMP quality control.
• Not tested on animals, Paraben-free, Eco-friendly.
Maoli Nano Immune Extreme Formula:
Designed to maximize the overall health and in particular the Immune System.
Serving size: 1ML per day. Shake well before use, Store away from heat/light/humidity, Keep away from children, Do not use when pregnant/breastfeeding, Always consult your physician before use.
Ingredients: MCT Coconut Oil, INDSCBD oil, Nano -Vitamine A, -Vitamine B5, -Vitamine B6, -Vitamine B12, -Vitamine C, -Koper, -Zink.
INDSCBD Oil Ingredients: Purified water, Broad Spectrum CBD oil, lipids, surfactants, fatty acids.
OUR IMMUNE SYSTEM: AN OVERVIEW
We are constantly exposed to infectious diseases, bacteria and viruses (antigens), all intent on running amok and wreaking havoc. Without any inbuilt defences to keep these invaders at bay, we’d all last about five minutes on this planet. Thank goodness we have an immune system: the complex network of cells, tissues and organs, running with military precision to keep us healthy.
A key player in the immune system’s arsenal are white blood cells or leukocytes, which seek out and destroy any unwanted visitors. Leukocytes can be divided into two groups: 1) lymphocytes (B cells and T cells) that destroy antigens and help the body to remember previous attackers; and 2) phagocytes that absorb and neutralize foreign intruders.
Many of us are familiar with T cells because of their relationship with the HIV virus, which wipes them out; this is what makes HIV patients vulnerable to normally harmless infections.
Our immune system also plays a key role in detecting malfunctioning cells inside our bodies, and, through the process of apoptosis or cell death, ensures that these cells do not continue to grow and become tumors.
Killing cells is a crucial element of a healthy functioning immune system, which maintains a delicate balance between growth and death. If, for example, there is too much cell death, autoimmune diseases can result, while too little can create the perfect environment for cancer.
Optimum immune function entails a complex balancing act that relies on constant communication between our immune cells, tissues, and organs. With the discovery of the endocannabinoid system (ECS) in the 1990s, scientists have found another key piece of the puzzle.
The endocannabinoid system comprises two main G protein-coupled receptors (CB1 and CB2), endogenous ligands known as endocannabinoids (anandamide and 2-AG), plus the proteins that transport our endocannabinoids and the enzymes that break them down in the body.
The ECS is a homeostatic regulator – continually working to maintain a state of biological balance.
Endocannabinoids are produced on demand, travelling backwards across chemical synapses and modulating cell activity. This partly explains why the ECS has been termed a homeostatic regulator – continually working to maintain a state of biological balance.
The ECS regulates a plethora of physiological processes, including immune function and inflammation. Both CB1 and CB2 receptors can be found on immune cells, although there are between 10-100 times more CB2 receptors than CB1. Endocannabinoids act upon immune cells directly through the CB2 receptor.
CB2 receptor activation creates an anti-inflammatory effect and is therefore a therapeutic target for autoimmune disorders and neurodegenerative disease.1 However, any ECS immunosuppressant activity is thought to be transient, and can be overridden when necessary in the presence of infection.2
Scientists know that plant cannabinoids like tetrahydrocannabinol (THC) and cannabidiol (CBD) impact our health by interacting in different ways with the endocannabinoid system. Thus, it makes sense that consuming medical cannabis will also directly affect our immune system. But researchers are struggling to understand exactly how.
Vitamin A (VitA) is a micronutrient that is crucial for maintaining vision, promoting growth and development, and protecting epithelium and mucus integrity in the body. VitA is known as an anti-inflammation vitamin because of its critical role in enhancing immune function.
Some studies reported that vitamin B5 (VB5) (pantothenic acid) can promote the expression of inflammatory cytokines in epithelial cells (17, 18). Thus, we hypothesized that VB5 could possibly enhance the inflammatory response of macrophages and further help the body to resist the MTB infection.
Vitamin B6 is in charge of keeping the immune system strong, making new red blood cells, and transporting oxygen throughout the body. Vitamin B has also been shown to improve migraines. Foods rich in pyridoxine are chicken, salmon, tuna, leafy greens, and chickpeas. Vitamin B6 deficiencies can cause mood changes and reduce antibodies needed to avoid infections. Vitamin B6 is responsible for producing white blood cells and T cells, which regulate immune responses. Vitamin B6 also helps the body make the protein interleukin-2 to direct white blood cell activity.
B12 plays an important role in white blood cell production, and white blood cells are essential for proper immune system functioning," says Middleberg. Not only can a lack of B12 lower your immunity, some immune system disorders can increase your likelihood of becoming deficient.
Ascorbic acid – the scientific name for pure Vitamin C – has been shown to support a vast number of immune mechanisms in your body. For example, your white blood cells are an important component of your immune system. You have several different types of white blood cell, each of which helps to fight off illness-causing viruses and bacteria in a different way. Vitamin C helps to stimulate both the production and function of many of these types of white blood cells. It also helps your body to produce important antibodies: proteins that bind invading microbes to neutralise them. And Vitamin C’s powerful antioxidant properties help to protect certain white blood cells from the toxic compounds they produce in their fight against pathogens. In other words, Vitamin C is an essential nutrient for healthy immune system response.
Copper is an essential trace mineral necessary for survival. It is found in all body tissues and plays a role in making red blood cells and maintaining nerve cells and the immune system. It also helps the body form collagen and absorb iron, and plays a role in energy production.
Zinc is found in cells throughout the body. It helps the immune system fight off invading bacteria and viruses. The body also needs zinc to make proteins and DNA, the genetic material in all cells. During pregnancy, infancy, and childhood, the body needs zinc to grow and develop properly.
All about CannaBinoiDs
Hemp/Cannabis has been used by civilizations all over the world for
thousands of years. The history of this plant goes as far back as 12,000 B.C.E. Written language developed on hemp paper, the first woven clothes were made of hemp fiber, and modern medicine evolved from extractions of hemp flowers. CBD is non-psychoactive. Scientific and clinical research suggests CBD’s potential as a treatment for arthritis, diabetes, alcoholism, MS, chronic pain, schizophrenia, PTSD, depression, antibiotic-resistant infections, epilepsy, and otherneurological disorders.
How could CannaBinoiDs work?
The human body’s EndoCannabinoid System produces naturally occurring cannabinoids, Anadamide and 2-AG(2-atachidonoylglycerol), which stimulate the body’s
cannabinoid receptors. Cannabinoid receptors (CB1, CB2, TRPV1, TRPA1 and TRPV4) are present on multiple cell types in the human skin (fibroblasts, keratinocytes, immune cells, neurons, subcutaneous fat cells and muscle layers). These receptors engage in “retrograde signaling,” that inhibits immune response, reduces inflammation, relaxes muscles, lowers blood pressure, increases blood flow and normalizes over-stimulated nerves. In the epidermis, CBD inhibits keratinocyte proliferation, decreases keratinization and suppresses cornified envelope formation, promotes epidermal differentiation, and inhibits proliferation of keratinocytes. Studies have also shown CBD can improve reduced barrier function, increase hydration, reduce moisture loss, inhibit dermal fibrosis, suppress UV-B induced skin damage, and decrease inflammation.